The Monash Freeway outbound exit ramp at Heatherton Road is closing for roadworks.
It will be shut from 7pm to 7am from Monday 17 July to Thursday 20 July.
Traffic will be detoured via Stud Road and can expect minor delays.
Workers will be installing cables to power new overhead electronic signs.
Between Wednesday 19 and Friday 21 July, the Monash Freeway will be closed in both directions between the South Gippsland Highway and Princes Highway.
The closure will be effective between 10pm and 4am inbound and 11pm to 5am outbound.